Tissue disposition of 54Mn in lead pretreated rats.

possible interactions between xenobiotics and their effect on human health has remained fragmentary. Industrial workers and the general population, overexposed to lead (Pb) in the work environment or through polluted biosphere, may also be exposed to other elements, both essential and nonessential. Zielhuis et al.1) reported increased blood manganese (Mn) levels with increased blood Pb in young children and occupationally exposed workers. Studies reported from our laboratory have shown significant alterations in neurochemical and behavioral